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Spaceflight may dramatically change the gut within weeks, causing bacteria to break down more protein as food moves more slowly through the intestines. The shift could help explain astronaut constipation and may have wider effects on health, making it an important concern for future missions to Mars.
NASA’s Office of the Chief Health and Medical Officer formed a working group in August 2026 to review the most recent data related to extravehicular activity (EVA) prebreathe testing and decompression sickness (DCS) events, venous thromboembolism (VTE) in-flight occurrences, and patent foramen ovale (PFO) implication as they relate to NASA’s Artemis (lunar and beyond) missions. The recommendations from this working group are built upon and integrate the outcomes of previous working groups hosted by OCHMO.
