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Science

Ozempic and Wegovy linked to rare risk of sudden vision loss

Popular diabetes and weight loss drugs such as Ozempic and Wegovy have been linked to a slightly increased risk of a rare condition that can cause sudden, potentially permanent vision loss. Although the risk remains very low, Rutgers researchers say the findings warrant attention as millions of people turn to GLP-1 medications.

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Health

Alzheimer’s risk gene APOE4 may have a reversible weakness

The Alzheimer’s risk gene APOE4 may actively damage brain blood vessels and sabotage the cellular systems that remove harmful proteins. Researchers were able to reverse some of these effects in experiments, revealing promising new targets for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases.

Science

Children at risk for depression get “stuck” on sad faces

Depression may change which emotional faces children notice most, but the pattern appears to depend on family history. Children at higher familial risk became increasingly focused on sad faces, while lower-risk children with rising symptoms paid less attention to happy ones.

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Health

A major risk of breast cancer screening may have been overestimated for decades

A new analysis suggests mammograms may lead to far less breast cancer overdiagnosis than some earlier studies indicated. Researchers reexamined all eight major randomized screening trials and accounted for differences in follow-up time, screening frequency, and screening after trials ended. Their results were consistent with an overdiagnosis rate below 5%, rather than estimates approaching 30% to 50%.

World

'Risk to humanity': At UN, tech leaders urge caution in AI development

The heads of major artificial intelligence firms pleaded with the United Nations on Wednesday to save the world or at least its people — by somehow regulating the fast-expanding technology that they have been designing. “If managed poorly, I even believe AI could be a risk to humanity as a whole,” said Dario Amodei, chief executive officer of Anthropic.

Science

Risk of Hydrazine Use Following Freeze–Thaw Exposure

For more information, contact Jonathan E. Jones, Langley Research Center, jonathan.e.jones@nasa.gov Download the PDF version The purpose of this Technical Bulletin is to communicate the risks associated with freeze–thaw cycles in hydrazine monopropellant systems and to provide general recommendations for mitigating damage, operational hazards, and loss of system reliability in propulsion and auxiliary hydrazine systems. […]