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enzyme

Health

This protective enzyme could help stop fatty liver disease from getting worse

Scientists have identified an enzyme that may act as a natural defense against the worsening of fatty liver disease, which affects an estimated 100 million Americans. The enzyme, called UBE2N, helps liver cells clear away damaged mitochondria and break down fat, potentially preventing the inflammation, scarring, and cell damage associated with the more dangerous condition MASH.

Science

This deep-sea enzyme survives heat that destroys most proteins

A deep-sea microbe uses an exceptionally heat-resistant enzyme to turn atmospheric nitrogen into ammonia at temperatures that would destroy most proteins. Its unusual structure and a newly observed reaction state may reveal an ancient, shared mechanism behind nitrogen fixation and could eventually inspire cleaner biotechnology and fertilizer production.